Use a slab-serif font (like Arvo or Memphis) for big headlines, page headlines and section headlines. Use a sans-serif font family (like Myriad Pro) for all subheadlines and body copy.
Consider using a condensed font for subheads. It helps create contrast, which makes the hierarchy of information easier for the reader to understand.
Do not use a slab-serif font for body copy. Do not use all caps for anything other than small actionable areas or short headlines.